We had the opportunity to present some of the work from our group recently at a Keystone Simposium conference held in Snowbird Resort, Utah (USA), March 27—30, 2022. «Cancer: Aging in the Driver’s Seat«, organized by Eiji Hara, Manuel Serrano, Judy Campisi and Sheila Stewart. It was a fantastic meeting with great talks by invited speakers and short talks selected from the abstracts. We gave a talk entitled «Reprogramming the cancer genome». We also had the opportunity to meet old friends and colleagues.