Manuel Collado is an I3-SNS investigator at the Health Research Institute of Santiago de Compostela (IDIS) where he leads the Cell Senescence, Cancer and Aging Laboratory since 2012. Before that, he obtained his PhD at UAM in Madrid in 1997 for work done at CNB (CSIC-UAM) and was a postdoctoral student, first at the Ludwig Institute for Cancer Research in London, UK, and later at NYU Medical School and at Memorial Sloan Kettering Cancer Center in New York, USA. He returned to Madrid, Spain, in 2001 to join Manuel Serrano´s group at CNB. The laboratory moved in 2003 to the Spanish National Cancer Research Centre (CNIO), where he worked for almost 9 years as staff scientist.
During his career, he has published more than 70 papers, several of them in high impact journal such as Nature (3 articles), Cell, Cancer Cell, Cell Stem Cell, PNAS, EMBO J, Genes & Development, Nature Communications, Aging Cell, Cancer Research, etc. He is also the author of some the most cited reviews in his field published in Nature Reviews Cancer (2 reviews) and Cell (2 reviews).
Along the years, his scientific work has been mainly focused on cancer and in particular tumor suppression mechanisms, working mainly on cell senescence. On this subject he has published more than 20 articles, among them the first in vivo description of oncogene-induced senescence in Nature (more than 1000 citations) or the identification of programmed cell senescence during embryo development (a “highly cited article” in his field according to Thompson´s Web of Science), and more recently the description of a new family of senolytic compounds (Nature Communications).